A very close friend of mine was accepted to UCSF, Duke, UPENN, Columbia and MIT last year, all for neuro. She really was one of the smartest people I have ever met, but as far as being the overachieving type, that wasn't her. She said she had an okay gpa from Princeton, psych major, perfect GRE, summer research in Mexico, 2 years of post bacc research at a top institution. I would say the thing that got her interviews at these schools was her LOR from her PI, who is very well known in the Alzheimer's disease field, it probably said something along the lines of "so and so is in my opinion a genius, one of the most creative people I have ever met and has on her own developed a novel method of distinguishing tauopathies from post mortem tissue."
What I'm trying to say is that these schools get all of the best applicants as far as statistics, and in my opinion awards and grades don't matter, what they are looking for is who can set themselves apart as a scientist.