neonEspresso

Have any Americans in biomedical fields done postdocs in Europe? I have been told it is seen by some as a step backwards (since so many people go Europe --> US), but I would love to apply to postdocs there, especially Germany and UK. Do people have general advice on this matter? How is it different from postdocing in the US? I am currently working on a neuroscience PhD at a highly ranked institution in the US.