Let's see...My main area of interest is in epistemology, esp. skepticism and the debate between epistemological naturalists and apriorists. Some of my best work during my MA was done on Quine's naturalized epistemology, and I ended up writing a 30+ page paper on the topic. I subsequently cut it down, but I still feel that it's not as focused as my paper on Plato's Theaetetus (which is about 24 pages), which is what I'm considering using for the majority of my schools. The paper on Plato's Theaetetus critically examines his self-refutation argument against Protagorean relativism. In brief, it's a paper on truth-relativism, couched in a historical context. Is this too far away from epistemology? I'm interested in ancient as a secondary interest, but mostly only insofar as it touches on issues like relativism and skepticism. (I'm interested, for example, in Sextus Empiricus and the relation between Pyrrhonian skepticism and infinitism in contemporary debates about justification).
Would you mention in your personal statement why your writing sample isn't directly in your primary stated interest, if that were the case?