specific aims help

[alek]

Hello,

 

I'm writing my specific aims page for my thesis project, and keep going in circles about what is fit to use as rationale for an aim. 

 

Basically, there's a morphogenetic signaling network A that I'm interested in, a structure B that I hypothesize it acts upon, and a cell behavior C which I know it influences. I'm trying to link the three, and say A regulates C through B. 

 

the problem is, there's data, but not concrete data, in our system suggesting that B matters to C,

and solid data that A regulates B...but in other organisms, in different tissue types. 

 

my committee keeps telling me i've got an interesting biological problem, but that my aims are terrible. 

my advisor isn't worried about them, and thinks it only matters how i tell the story. 

but i'm worried that i dont even know where the threshold is, in terms of jumping to conclusions to make logical connections...

how much is too much?