NSF and translational medicine?

[persimmony]

I know NSF is more focused on basic science research, but they do have Biomedical Engineering listed as a choice for the primary field. I've also heard they make exceptions to the no translational medicine rule if you are a BME student. I am a 2nd year in a BME lab, but our work is more engineering "in principal." Basically we are a genome editing lab that develops and uses new CRISPR constructs for genetic diseases.

To be more specific, one of my main projects is using CRISPR to differentiate pluripotent stem cells into other tissue stem cells ultimately, for human disease relevant purposes. Even if my application is sent to Biomedical Engineers, would this work be TOO translational and be denied immediately?