1.) I've been working in the tissue typing lab for 5 years working with HLA histocompatability and the organ transplant program at a hospital. I'd ideally like to target investigations into preventative measures to keep people from needing to go through a tedious process of the organ procurement/donation system, dialysis for 10+ years, or basically almost dead and in need of a heart liver or bone marrow transplant.
2.) I think depending upon your institution what ever "track" you end up going down post-doc. If it be the "academic track" or the "research track" many universities require you to have a high output from your lab while also maintaining other academic responsibilities and (if at a hospital) clinical duties.
3.) I don't have a lot of experience with microbes, so my favorite protein would be anti-HLA antibodies!!!!!!!!!!!!!!! They are sneaking little suckers some times causing HUGE problems.
4.) I've spent a lot of time with the solid phase immunoassay luminex platform. If you aren't familiar with it, the platform basically uses flow cytometric principles in a micro scale with patented beads. You can basically customize any assay as long as you can attach the protein to the bead surface.
5.) I designed and validated my own luminex assay that we are bring into clinical use (pretty awesome in my book!)
So far it sounds like we are all in this for great reasons. I mean, just to get through this application process takes enough out of you!