Endnote did not work for me. I finally found a workable system using Papers to manage my research/citations and Scrivener to collect drafts and notes. You should give Endnote a try if it appeals to you. The ThesisWhisperer website (http://thesiswhisperer.com/) wrote several posts on her evolving work management. That's how I found Papers which is 100 times better for me than Endnote. Plus, I know several people who had Endnote crash on them at crucial moments.