My GPA is pretty low, only 3.10 cumulative in undergrad and 3.33 for my major. I also got a D in Intro to Electrical Engineering (my major was electrical engineering).
In the first masters program I went to I got a 2.7 GPA (was there only a semester, I had other issues, and got no degree) and they decided, even though I paid them quite a bit, to not send out transcripts to all the schools I applied to.
This is my killer issue since everything else is pretty good.