I won't go into too much detail, but I have a history with mood disorders too. I used to be a school teacher, and went to grad school to change careers because I was having daily panic attacks in my classroom. So I'm sensitive to that sort of thing too. I worked for 2 years between my finishing bachelors degree and starting my MS program. I'm in my second year in an MS psychology program and plan to get a PhD in neuroscience. When I entered my program I was freaking terrified. I had a bad case of impostor syndrome ("I don't belong here! As soon as they figure out that I'm an idiot they'll be kicking me out!") for almost the whole first year. That problem has just started to back off, and now I'm anxious about applying to PhD programs, getting my thesis on track, and attending SfN for the first time (big, scary, expensive conference). So I'm not going to lie to you: grad school is hard, it's a lot of work, a lot of deadlines, a lot of pressure. But here's the thing... EVERYONE is anxious. Anxiety, at least for me, ends up being a feedback loop: I'm anxious because there is a lot on my plate, and then I have the false perception that everyone around me is handling the workload better than I am. The perception that no one else is anxious about their workload except for me causes me more anxiety... and it spirals. I end up feeling stupid, unproductive, unprepared, and just generally like crap. Talking to other people in my program about their workload, how they handle it, and where they are in the process of preparing applications and writing their theses makes me feel so much better, because they are all just as worried as I am. That stops the feedback loop in it's tracks: I'll still be anxious about my work, but it can't spiral down into negative self-talk because I know my anxiety level is average, and so it can't make me any less effective or less intelligent or less productive than the rest of my cohort. So my advice is to make some friends in your program and schedule time to drink beer and bitch about it. It is more than likely you'll find out that everyone you know (except that one overachieving person who brags about how on top of shit they are- and screw that person, okay?) is having a lot of the same feelings you are, and that might make you feel a lot better about it. If you think your anxiety level might end up in the unhealthy range, why not start building a relationship with a therapist now so that they are familiar and trusted when you need them later?