@bioeng2016 It usually does help to have somewhat of a focused area of research as an undergrad, especially if it's relevant to your proposed area of research in the application. I've heard of many students with perfect numbers and qualifications get rejected cause their experience isn't a good "fit" for the type of research they want to do in graduate school. I think it would be better to propose an area of research that's closer to what you've done, then change the area once you get in. Especially since tissue engineering is the most popular field and you'd be competing with so many other people who have done tissue engineering for years.