1) I'm not sure yet. Either obtain a position in the US or go back to Europe and try to find something there. I know it's not easy to find jobs in this field.
2) I don't have specific works in mind yet. In my country (The Netherlands), comparative literature programs are in general more focused on critical and interdisciplinary approaches to literature (critical theory/cultural analysis), while 'national literature' departments like English or Dutch are more 'traditional' in the sense that there is more emphasis on literary history/'the canon' of a specific national sphere. Maybe it's different in the US.
The languages I would be able to work in are English, Dutch and (to a lesser extent) German and French. Focusing on anglophone literature/media alone would definitely be possible for me, although that seems overly limiting to me. Do English departments allow students to research translated works of literature? Is it in general necessary to read literary works in their original language, for Comparative Literature programs as well?