After seeing all of these stats, I'm expecting this to be a "fun"/stressful application season. As per the question of safety schools, I'm actually planning on taking a year and applying to medical school if I don't get accepted to the programs I applied to.
To facilitate the discussion, I guess I'll give my numerical stats:
GRE: 1400 composite (>700 quant)
GRE Chem: 95%
GPA: 4.0 at R1 university
~10 grad courses
3 years of research (2 different research groups)
1 summer research project
1 publication in a specialized journal (not 1st author...)
My letters will be great.
We shall see if these are good enough for where I applied.