Yeah, some "backwoods" parts of SC can be pretty awful, but Clemson and most all universities will treat you with equality and respect. I don't go to Clemson but I also go to school "in the middle of nowhere" and the international students are a big part of the social scene (well, the ones that want to be): Europeans, Asians, Africans, everyone.
But a word of advice for SC: just be on your guard if you are in sketchy, impoverished places with a mostly white population. Or just avoid them entirely.