To echo the last poster, the weather is for the most part great, but also totally unpredictable. If you can handle that then you will be fine (think four seasons in a day from time to time). There have been years where a big blizzard hits in October with 12+" of snow, then the rest of the winter we won't get more than 12" combined and it's into the 60's on Christmas. What you can rely on is that there will be 300+ days of sunshine, it will be fairly dry year-round (good if you are prone to asthma/lung problems), and cold snaps will last a week at most.
If you are into any type of outdoor activities like hiking, biking, camping, skiing, etc then you'll be in one of the best spots in the US. Even if you aren't, the proximity and access to those means you might pick up a new hobby. There are also a good number of natural hot springs up in the mountains which make for good day trips/weekend excursions. For beer lovers there are the already mentioned microbreweries as well as this: http://www.greatamericanbeerfestival.com/
An added benefit is that Denver International Airport is very accessible with direct flights to nearly everywhere in the country. United, Southwest, and Frontier are the main carriers. It's a minor thing but really convenient that you don't need to drive 2 hours to the airport whenever you have a trip.