God, yes. My undergrad wasn't in English, and since I'm finishing up an MA in writing, my contemporary knowledge is good, but not the classics. I scored a 90% on my verbal GRE and a dismal 23% on my Literature subject test. It's so terrible it's almost funny, in a way.
I applied to USC and University of Denver as well as some other Literature programs without a creative focus. Maybe they won't pay too much attention to the subject test...