Skype is hard! Just had mine, and was thrown off by it. It is much harder to read body language cues, to get a feel for the room, to make any meaningful eye contact… I also felt like there was a "Let's cut to the chase" vibe, which makes a ton of sense but is also a bit sterile. It was only 25 minutes, and I think the first 10 felt like a warm-up. I babbled. Not happy about that! It seemed to run more smoothly when I got them talking (not surprising), and having a few key questions is a real must. The above post is great. I also said something along the lines of "I am familiar with some of what you've done, and I'm interested to know future directions for your research…" I also needs some logistics answered, and was glad I asked.
Overall, were I to do it again, I would find a far more succinct, confident way of stating my research interests. It is a softball question, and there is no excuse for stumbling over it as I did. I was more nervous than I expected...
Lesson learned!