I've had professors respond and gotten rejected/waitlisted (UW). I've also had professors not respond and gotten accepted (MIT). I think it's more concerning to not get a response in a direct-admit program. Rotation-based programs it seems less concerning.
Especially right now where schools/departments are scrambling to deal with COVID-19, a lot of professors are going have delayed/forgotten responses. A late/lack of response is not the end of the world.