I am applying for this cycle, so take my advice with a grain of salt.
Most Ph.D. and M.S. programs in statistics seem to understand that many incoming students will have limited experience with statistical coursework. Many only require a single statistics class for admission, or just 'exposure', even in the top 20 range. If you have taken econometrics this may suffice for 'exposure' at some schools. A B or (especially) below in this course could damage your application to some top programs.
You have not commented on your mathematical background, but that will be far more important. Ensure you have strong grades in multivariable calculus and matrix algebra, as well as any other upper level math, and do well on the GRE. Masters programs are becoming increasingly competitive each year, but they are still not extremely challenging to get into, granted you are not aiming for funding.
In short, take it if you can do well, but don't take it if you can't nail an A, in my opinion.
Also, the sticked post by cyberwulf regarding personal statements may be of use to you: